This is a daily pill that lowers testosterone levels and blocks testosterone from working. ![]() Use of testosterone blockers (in addition to estradiol) increases the likelihood that someone may experience decreased libido and/or erectile dysfunction, more on that here.įOLX offers two main categories of anti-androgens, and two types of Progesterone, each of which can be taken at different dosage levels, based on personal preference. If unclear about which progesterone to take, we recommend Prometrium since it may be safer than other forms of progesterone. Overall, the response to progesterone is often very individualized, with some noticing benefits and others not noticing any benefits or noticing only negative effects. Some people also report improvement in mood and libido, while others report a worsening. There may be some testosterone blocking effect of progesterone. Some clinicians have found that progesterone may be helpful to improve breast or areolar development only if you don’t achieve full breast development with estrogen. What is known is inconclusive: some studies suggest that progesterone does not help with breast development or body fat redistribution, and it may increase the risks of estrogen. ![]() Unfortunately, there is not a lot known about progesterones and how they affect overall changes in people undergoing Estrogen HRT because it has not been studied well. Why progesterone?įewer folx choose to take Progesterone in addition to estrogen and anti-androgens, and most people who decide to try progesterone wait to start until about a year after they start estrogen. Because estradiol decreases the amount of testosterone produced by a body over time, some people are able to eventually stop using anti-androgens. So anti-androgens work to block the effects of androgens such as testosterone. Those born with XY chromosomes and/or assigned male at birth often have high levels of androgens, while those born with XX chromosomes and/or assigned female at birth often have low levels of androgens (and high levels of estrogens). ![]() "Androgens" are hormones that regulate the development of sex characteristics.
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